1-EBIO

CAS: 10045-45-1

Ref. 3D-FE125049

Product Information

• Name: 1-EBIO
• Synonyms: 1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one, 1-Ebio, 1-Ethyl-1,3-dihydrobenzimidazol-2-one, 1-Ethyl-2,3-dihydro-1H-1,3-benzodiazol-2-one, 1-Ethyl-2-benzimidazolinone, 1-Ethyl-2-oxo-2,3-dihydrobenzimidazole, 1-Ethylbenzimidazolinone, 1-ethyl-1,3-dihydro-2H-benzimidazol-2-one, 2-Benzimidazolinone, 1-ethyl-, 2H-Benzimidazol-2-one, 1-ethyl-1,3-dihydro-, 3-Ethyl-1H-benzimidazol-2-one, 3-Ethyl-2-benzimidazolinone, 1-Ethylbenzimidazolin-2-one

Description

1-EBIO is a pharmacological agent that inhibits the mitochondrial membrane potential. It has been shown to have low potency against infectious diseases, but high potency against pluripotent cells. 1-EBIO is an apical cation channel blocker that has been shown to inhibit the activity of whole-cell recordings in cells infected with HIV and other pathogens. It is also a potent inhibitor of cellular physiology, which may be due to its ability to inhibit the production of cytokine IL-2 receptor, a protein necessary for cell proliferation. 1-EBIO blocks cytosolic Ca2+ levels in hl-60 cells by inhibiting mitochondrial membrane potential through binding to dinucleotide phosphate (DNP).

• Brand: Biosynth

Chemical properties

• Molecular weight: 162.19 g/mol
• Formula: C₉H₁₀N₂O
• Purity: Min. 95%
• InChI: InChI=1S/C9H10N2O/c1-2-11-8-6-4-3-5-7(8)10-9(11)12/h3-6H,2H2,1H3,(H,10,12)
• InChI key: InChIKey=CXUCKELNYMZTRT-UHFFFAOYSA-N
• SMILES: CCn1c(=O)[nH]c2ccccc21