Exametazime

CAS: 105613-48-7

Ref. 3D-FE167140

Product Information

• Name: Exametazime
• Synonyms: (+-)-(3RS,3'RS)-3,3'-((2,2-Dimethyltrimethylene)diimino)di-2-butanone (E,E)-dioxime, 2-Butanone, 3,3'-((2,2-dimethyl-1,3-propanediyl)diimino)bis-, dioxime, (R*,R*-(E,E))-(+-)-, 2-Butanone, 3,3'-((2,2-dimethyl-1,3-propanediyl)diimino)bis-dioxime-(sup 99m)Tc, 2-Butanone, 3,3′-[(2,2-dimethyl-1,3-propanediyl)diimino]bis-, 2,2′-dioxime, (2E,2′E,3R,3′R)-rel-, 2-Butanone, 3,3′-[(2,2-dimethyl-1,3-propanediyl)diimino]bis-, dioxime, (2E,2′E,3R,3′R)-rel-, 2-​ Butanone, 3,​ 3'-​ [(2,​ 2-​ dimethyl-​ 1,​ 3-​ propanediyl)​ diimino]​ bis-​ , 2,​ 2'-​ dioxime, (2E,​ 2'E,​ 3R,​ 3'R)​ -​ rel-, Ceretec, Exametazima, Exametazima [Spanish], Exametazimum, Exametazimum [Latin], Hexametazime, Hexametazine, Hexamethylpropylene amine oxide, Hmpao, N,N'-bis[(2R,3E)-3-(hydroxyimino)butan-2-yl]-2,2-dimethylpropane-1,3-diamine, Technetium Tc99m Exametazime, Unii-G29272Nckl, d,1-Hexamethylpropylene amine oxime-(sup 99m)Tc, dl-HMPAO, dl-Hexamethylpropylene amine oxide

Description

Exametazime is a diagnostic agent used in the diagnosis of inflammatory bowel disease. It is a prodrug that is metabolized to its active form, examethasone, in the body. Exametazime can be used to assess disease activity and determine the need for treatment. The diagnostic use of this drug has been shown to be effective in both radiation-induced and chemotherapy-induced changes. Exametazime may also be useful in the treatment of brain damage caused by stroke or head injury. This drug has been found to possess anti-cancer properties, which have been demonstrated by its ability to inhibit tumor growth in rats. Exametazime has also been shown to reduce symptoms associated with Crohn's Disease as well as other forms of bowel disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 272.39 g/mol
• Formula: C₁₃H₂₈N₄O₂
• Purity: Min. 95%
• InChI: InChI=1S/C13H28N4O2/c1-9(11(3)16-18)14-7-13(5,6)8-15-10(2)12(4)17-19/h9-10,14-15,18-19H,7-8H2,1-6H3/b16-11+,17-12+/t9-,10-/m1/s1
• InChI key: InChIKey=BPNZYADGDZPRTK-UDUYQYQQSA-N
• SMILES: C/C(=N\O)[C@@H](C)NCC(C)(C)CN[C@H](C)/C(C)=N/O