E 7386
CAS: 1799824-08-0
Ref. 3D-FE167967
| 1mg | To inquire | ||
| 50µg | To inquire | ||
| 100µg | To inquire | ||
| 250µg | To inquire | ||
| 500µg | To inquire |
Product Information
E 7386 is a monoclonal antibody that targets β-catenin, which is found in the cytoplasm of cells. E 7386 binds to β-catenin and inhibits its interaction with the transcription factor LEF1, preventing it from binding to DNA. In addition, E 7386 has been shown to inhibit epidermal growth factor (EGF) signaling and potentiate tumor cell death by inducing apoptosis. E 7386 has also been shown to reduce microvessel density and increase tumor cell death in mouse xenografts. It is currently being used for treatment of colorectal carcinoma and other cancers.
Chemical properties
Technical inquiry about: 3D-FE167967 E 7386
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