3D-FE168252 - ethyl-isocyanide | 624-79-3

1-(4-Chlorophenyl)ethyl isocyanide

1-(5-Methyl-2-thienyl)ethyl isocyanide

1-(3-Chlorophenyl)ethyl isocyanide

Versatile small molecule scaffold

Diphenylmethyl isocyanide

Ethyl isocyanoacetate is used in the syntheses of 7-aza-tetrahydroindoles, oxazolines, benzodiazepines, imidazoles and oxazoles. For example, it is involved in the synthesis of 1H-indole-2-carboxylate by condensing with 2-bromo benzenealdehyde using CuI as a catalyst. It is a precursor used in the p

Ethyl isocyanoacetate

Ethyl-2-isocyanoacetate is a chemical substance that is used in organic chemistry as a reagent for the synthesis of esters and amides. It has been shown to have strong antimicrobial activity against bacteria, including methicillin-resistant Staphylococcus aureus. This compound has also been shown to inhibit the growth of skin cancer cells, which may be due to its ability to induce apoptosis. Ethyl-2-isocyanoacetate reacts with nitro groups in proteins and amino acids by replacement of an oxygen atom from the hydroxyl group with a nitrogen atom from the carboxylic acid group. This reaction mechanism is catalyzed by ns3 protease, which is activated by hydrogen peroxide and thioredoxin reductase.