BRD 0705

CAS: 2056261-41-5

Ref. 3D-FE171001

Product Information

• Name: BRD 0705
• Synonyms: (S)-4-Ethyl-7,7-dimethyl-4-phenyl-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one
• Brand: Biosynth
• Description: BRD 0705 is a potent inhibitor of autophagy that targets the protein ATG3. This compound was shown to inhibit proliferation and induce apoptosis in cancer cells, as well as reducing the number of β-cells in the pancreas. The mechanism for BRD 0705's effects on cell death may be through its ability to inhibit splicing and promote nonsense-mediated decay of mRNAs, which leads to reduced protein synthesis, cell death, and tumorigenesis.; BRD 0705 has also been shown to be effective against human diabetes due to its ability to inhibit β-cell death by inhibiting autophagy.

Chemical properties

• Molecular weight: 321.42 g/mol
• Formula: C₂₀H₂₃N₃O
• Purity: Min. 95%