Emetine

CAS: 483-18-1

Ref. 3D-FE22663

Product Information

• Name: Emetine
• Synonyms: 6',7',10,11-Tetramethoxy-emetanEmetine(-)-Emetine, (2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-2H-benzo[a]quinolizine, 2H-Benzo(a)quinolizine, 3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-((1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolyl)methyl)-, 2H-Benzo[a]quinolizine, 3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-, (2S,3R,11bS)-, 6',7',10,11-Tetramethoxyemetan, Brn 0100829, Cephaeline methyl ether, Cephaline-O-methyl ether, Emetan, 6',7',10,11-tetramethoxy-, Emetan, 6′,7′,10,11-tetramethoxy-, Emetin, Emetina, Emetine [BAN], Hsdb 2150, Methyl cephaeline, Nsc-33669, Unii-X8D5Epo80M, (-)-Emetine, Emetine

Description

Alkaloid from the roots of the tropical plant Cephaelis ipecacuanha and active ingredient in ipecac. The compound is an inhibitor of protein synthesis and DNA replication. It prevents the formation of Okazaki fragments and uncouples leading and lagging strands during DNA replication. Ementine therefore selectively inhibits the lagging strand synthesis and prevents ADP-ribosylation in the S-phase of cell cycle. It can be used for the preparation and of newly synthesised DNA. The compound has been also used as antiprotozoal agent for the treatment of ameboasis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 480.64 g/mol
• Formula: C₂₉H₄₀N₂O₄
• Purity: 90%Min