(+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine

CAS: 82717-96-2

Ref. 3D-FE22880

Product Information

• Name: (+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine
• Synonyms: (a-S)-a-[[(1S)-1-carboxyethyl]amino]benzenebutanoic Acid, (2S)-2-{[(1R)-1-(ethoxycarbonyl)-3-phenylpropyl]ammonio}propanoate, (N-(s)-ethoxy Carbonyl-3-Phenyl Propyl) L-alanine, (S,S)-N-(1-EthoxyCarbonyl-3-PhenylPropyl)Alanine, Benzenebutanoic acid, α-[(1-carboxyethyl)amino]-, monoethyl ester, [S-(R*,R*)]-, Benzenebutanoic acid, α-[[(1S)-1-carboxyethyl]amino]-, 1-ethyl ester, (αS)-, Benzenebutanoic acid, α-[[(1S)-1-carboxyethyl]amino]-, monoethyl ester, (αS)-, Ecppa, N-[(1R)-1-(ethoxycarbonyl)-3-phenylpropyl]-D-alanine, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanine, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]alanine, N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine, N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-<span class="text-smallcaps">L</span>-alanine, N-[1(S)-Ethoxycarbonyl-3-phenylpropyl]-<span class="text-smallcaps">L</span>-alanine, N-[1-(S)-ethoxy carbonyl-3-phenylpropyl]-L-alanine, N~6~-(trifluoroacetyl)lysine

Description

(+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine is an impurity of enalaprilat, which is a pharmaceutical drug used in the treatment of hypertension. Enalaprilat is manufactured by reacting 1-(S)-ethoxycarbonxyl-3-phenylpropane with L-alanine and triphosgene. This impurity has been shown to be a potent inhibitor of the enzyme angiotensin converting enzyme (ACE) and may cause adverse effects such as hypotension, cough, and dizziness. The chemical structure of (+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine consists of an aliphatic hydrocarbon chain with a maleate group at one end and a benzyl group at the other end. It also contains two amines, one on each side of the molecule.

• Brand: Biosynth

Chemical properties

• Molecular weight: 279.33 g/mol
• Formula: C₁₅H₂₁NO₄
• Purity: Min. 95%
• Color/Form: Powder