(+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine

CAS: 82717-96-2

Ref. 3D-FE22880

Product Information

• Name: (+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine
• Synonyms: (a-S)-a-[[(1S)-1-carboxyethyl]amino]benzenebutanoic Acid
• Brand: Biosynth
• Description: (+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine is an impurity of enalaprilat, which is a pharmaceutical drug used in the treatment of hypertension. Enalaprilat is manufactured by reacting 1-(S)-ethoxycarbonxyl-3-phenylpropane with L-alanine and triphosgene. This impurity has been shown to be a potent inhibitor of the enzyme angiotensin converting enzyme (ACE) and may cause adverse effects such as hypotension, cough, and dizziness. The chemical structure of (+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine consists of an aliphatic hydrocarbon chain with a maleate group at one end and a benzyl group at the other end. It also contains two amines, one on each side of the molecule.

Chemical properties

• Molecular weight: 279.33 g/mol
• Formula: C₁₅H₂₁NO₄
• Purity: Min. 95%
• Color/Form: Powder