Ethyl (2R,4R)-4-methylpipecolate

CAS: 74892-82-3

Ref. 3D-FE22918

Product Information

• Name: Ethyl (2R,4R)-4-methylpipecolate
• Synonyms: (2R-trans)-4-Methyl-2-piperidinecarboxylic acid ethyl esterEthyl (2R,4R)-4-methyl-2-piperidinecarboxylate(2R,4R)-4-Methyl-2-piperi dinecarboxylic acid ethyl ester, (2R,4R)-4-Methyl-2-piperidinecarboxylic acid ethyl ester, (2R,4R)-ethyl 4-methylpiperidine-2-carboxylate, (2R,4R)-ethyl-4-methyl-2-Piperidinecarboxylate, 2-Piperidinecarboxylic acid, 4-methyl-, ethyl ester, (2R,4R)-, 2-Piperidinecarboxylic acid, 4-methyl-, ethyl ester, (2R-trans)-, ethyl (2R,4R)-4-methylpiperidine-2-carboxylate

Description

Ethyl (2R,4R)-4-methylpipecolate is an organic compound that can be synthesized from the reaction of ethyl 2-bromoacetate and 4-methylphenol. It has been used as a precursor to medicines and intermediates. The reaction can be carried out in an alkaline environment at high temperature with a transfer catalyst, such as palladium on charcoal. The reaction time is dependent on the efficiency of the transfer and microreactor. Ethyl (2R,4R)-4-methylpipecolate is hydrolyzed to give 2-(ethoxycarbonyl)propionic acid by hydrolysis with water or base.

• Brand: Biosynth

Chemical properties

• Molecular weight: 171.24 g/mol
• Formula: C₉H₁₇NO₂
• Purity: Min. 95%
• Color/Form: Colourless to light yellow liquid.