Product Information
Name:R-(+)-Etomoxir
Synonyms:
- (R)-2-[6-(4-Chlorophenoxy)hexyl]oxiranecarboxylic acid
- ethyl ester
Brand:Biosynth
Description:Etomoxir is a potent inhibitor of the mitochondrial enzyme, fatty acid: 2-enoyl-CoA reductase. This enzyme catalyzes the conversion of long-chain acyl-CoA to acetyl-CoA, which is required for the synthesis of mitochondrial membrane phospholipids and cardiolipin. Etomoxir inhibits this activity and consequently prevents the production of ATP. It also inhibits oxidative phosphorylation in isolated mitochondria and reduces locomotor activity in rats. Etomoxir has been shown to have inhibitory properties on human malignant brain cells as well as breast cancer cells (MDA-MB-231).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:326.81 g/mol
Formula:C17H23ClO4
Purity:Min. 95%
InChI:InChI=1S/C17H23ClO4/c1-2-20-16(19)17(13-22-17)11-5-3-4-6-12-21-15-9-7-14(18)8-10-15/h7-10H,2-6,11-13H2,1H3/t17-/m1/s1
InChI key:InChIKey=DZLOHEOHWICNIL-QGZVFWFLSA-N
SMILES:CCOC(=O)[C@@]1(CCCCCCOc2ccc(Cl)cc2)CO1