Ergocornine

CAS: 564-36-3

Ref. 3D-FE30655

Product Information

• Name: Ergocornine
• Synonyms: 12'-Hydroxy-2',5'-a-bis(1-methyl-ethyl)ergotaman-3',6',18-trione
• Brand: Biosynth
• Description: Ergocornine is an ergoline alkaloid, which is a naturally occurring compound found in ergot fungi, specifically Claviceps species. These fungi predominantly infect cereal grains such as rye, leading to the production of a variety of ergot alkaloids. Ergocornine acts mainly by interacting with adrenergic receptors, displaying affinity for both alpha-adrenergic and serotonin receptor subtypes. This interaction results in vasoconstrictive and neuromodulatory effects, primarily impacting vascular and smooth muscle tissues.Ergocornine and related alkaloids have been studied extensively for their pharmacological properties. They are of particular interest due to their potential applications in treating conditions such as migraines, where the vasoconstrictive properties can mitigate the symptoms. Additionally, their effects on smooth muscles make them candidates for research in uterine contraction regulation during labor. However, due to the potent nature of these compounds and potential for toxicity, their clinical applications require careful consideration of dosage and delivery systems. Scientists continue to explore ergocornine's pharmacodynamics to better understand its therapeutic potential and safety profile.

Chemical properties

• Molecular weight: 561.67 g/mol
• Formula: C₃₁H₃₉N₅O₅
• Purity: Min. 95%
• InChI: InChI=1S/C31H39N5O5/c1-16(2)26-28(38)35-11-7-10-24(35)31(40)36(26)29(39)30(41-31,17(3)4)33-27(37)19-12-21-20-8-6-9-22-25(20)18(14-32-22)13-23(21)34(5)15-19/h6,8-9,12,14,16-17,19,23-24,26,32,40H,7,10-11,13,15H2,1-5H3,(H,33,37)/t19-,23-,24+,26?,30-,31+/m1/s1
• InChI key: InChIKey=UJYGDMFEEDNVBF-CETVIHQBSA-N
• SMILES: CC(C)C1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C=C4c5cccc6[nH]cc(c56)C[C@H]4N(C)C3)(C(C)C)C(=O)N12