2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole trihydrochloride
CAS: 875756-97-1
Ref. 3D-FE36315
25mg | 144.00 € | ||
50mg | 217.00 € | ||
100mg | 325.00 € | ||
250mg | 454.00 € | ||
500mg | 681.00 € |
Product Information
- Hoechst 33342 trihydrochloride
2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole trihydrochloride (EPMB) is a DNA binding agent that is used in tumor detection and research into apoptosis. It has been shown to inhibit the activity of p-glycoprotein, which is an efflux pump protein, and Bcl-2 protein. EPMB has also been shown to cause apoptosis in human squamous cell carcinoma cells in a concentration dependent manner. This compound has shown potential as a treatment for cancer because it inhibits the ability of cancer cells to proliferate by binding to the NMDA receptor.
Chemical properties
Technical inquiry about: 3D-FE36315 2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole trihydrochloride
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