trans-Ethyl 4-bromocrotonate

Ref. 3D-FE36836

Product Information

• Name: trans-Ethyl 4-bromocrotonate
• Synonyms: (E)-Ethyl 4-bromocrotonate
• Brand: Biosynth
• Description: Trans-ethyl 4-bromocrotonate is an organic compound that belongs to the class of aldehydes. It is used as a building block in the synthesis of indole-3-pyruvic acid and other β-amino acids, which are biologically active compounds. Trans-ethyl 4-bromocrotonate can be prepared by reacting allyl bromide with ethyl acetoacetate in the presence of hydrochloric acid and sodium salts. The reaction proceeds efficiently at room temperature, making it an efficient method for the preparation of this compound. Trans-ethyl 4-bromocrotonate has been shown to inhibit the activity of pancreatic lipase and may also inhibit other enzymes such as cholesterol esterase or lecithinase. This inhibition activity may be due to its ability to act as an acceptor for halides in these reactions.

Chemical properties

• Molecular weight: 193.04 g/mol
• Formula: C₆H₉BrO₂
• Purity: Min. 95%
• Color/Form: Liquid
• InChI: InChI=1S/C6H9BrO2/c1-2-9-6(8)4-3-5-7/h3-4H,2,5H2,1H3/b4-3+
• InChI key: InChIKey=FHGRPBSDPBRTLS-ONEGZZNKSA-N
• SMILES: CCOC(=O)/C=C/CBr