Ethyl 3-chloromethylbenzoate
CAS: 54589-54-7
Ref. 3D-FE37024
| 10g | Discontinued | ||
| 25g | Discontinued | ||
| 50g | Discontinued | ||
| 100g | Discontinued |
Product Information
Name:
Ethyl 3-chloromethylbenzoate
Synonyms:
- 3-(Chloromethyl)benzoic acid ethyl ester
- Benzoic acid, 3-(chloromethyl)-, ethyl ester
- Ethyl 3-(Chloromethyl)benzoate
- Ethyl m-(chloromethyl)benzoate
Description:
Ethyl 3-chloromethylbenzoate is an ester prodrug of acyclovir that is hydrolyzed to the active form in human plasma. It is a prodrug, which means that it is not the biologically active form of acyclovir. The ester bond in ethyl 3-chloromethylbenzoate is cleaved by hydrolysis, releasing the carboxylic acid and ethyl alcohol. The carboxylic acid is then converted to acyclovir by oxidation. Acetylation of the 3-position on the benzene ring increases its stability and enhances water solubility, making it more suitable for topical administration. The half life of ethyl 3-chloromethylbenzoate in humans has been shown to be 5 hours, which makes it more suitable for once daily dosing as opposed to other prodrugs with half lives as short as 1 hour.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
