Product Information
Name:Epinastine
Brand:Biosynth
Description:Epinastine is a drug that is used for the treatment of chronic cough, chronic allergic rhinitis, and vasomotor rhinitis. It is a histamine H1 receptor antagonist. Epinastine has no significant effects on beta-adrenergic receptors or muscarinic receptors. Epinastine binds to the DNA of human cells and inhibits the transcription of mRNA from the DNA to prevent protein synthesis. It also has an inhibitory effect on recombinant cytochrome P450 enzymes and reduces the rate constant of these enzymes by more than 50%. The binding affinity of epinastine to purified recombinant cytochrome P450 enzymes was determined using fluorescence polarization assay. Epinastine also inhibits eosinophil cationic protein release in response to benzalkonium chloride and suppresses two-way crossover (2WC) reactions in vitro.
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Chemical properties
Purity:Min. 95%