2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline

CAS: 16357-59-8

Ref. 3D-FE40640

Product Information

• Name: 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline
• Brand: Biosynth
• Description: 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinolin, also known as EEDQ, is a peptide coupling reagent used to couple acyl amino acids to amino acid esters. EEDQ can be used in a one-step procedure in solution and solid-phase synthesis, achieving good yields with suppression of racemisation. EEDQ is used in the formation of antibody-drug conjugates and DNA-encoded bioconjugates formed from the reaction of an amine, a carboxylic acid and a DNA fragment. EEDQ is also an irreversible dopamine-receptor antagonist (see N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline for Pharmaceutical and Diagnostic Industries).

Chemical properties

• Molecular weight: 247.29 g/mol
• Formula: C₁₄H₁₇NO₃
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3
• InChI key: InChIKey=GKQLYSROISKDLL-UHFFFAOYSA-N
• SMILES: CCOC(=O)N1c2ccccc2C=CC1OCC