R-(-)-Ethyl nipecotate

CAS: 25137-01-3

Ref. 3D-FE44423

Product Information

• Name: R-(-)-Ethyl nipecotate
• Synonyms: (-)-Ethyl nipecotate, (-)-Nipecotic acid ethyl ester, (3R)-(-)-Ethyl nipecotate, (3R)-3-Piperidinecarboxylic acid ethyl ester, (R)-3-Piperidinecarboxylic acid ethyl ester, (R)-Ethyl nipecotate, (R)-Ethyl piperidine-3-carboxylate, (R)-Nipecotic Acid Ethyl Ester, 3-Piperidinecarboxylic acid, ethyl ester, (R)-, 3-piperidinecarboxylic acid, ethyl ester, (3R)-, Ethyl (3R)-piperidine-3-carboxylate, Ethyl (3R)-piperidinecarboxylate, Ethyl (R)-3-piperidinecarboxylate, Ethyl (R)-nipecotate, Nipecotic acid, ethyl ester, (R)-(-)-

Description

R-(-)-Ethyl nipecotate is a chiral molecule that has been shown to inhibit serine proteases. The enantiopure form of this compound was found to be more potent in inhibiting the activity of inflammatory enzymes than the racemic mixture. R-(-)-Ethyl nipecotate also inhibits uptake of these enzymes, which may be due to its ability to inhibit membrane transport proteins. In addition, R-(-)-Ethyl nipecotate has been shown to have an inotropic effect on rat heart muscle and may act as an inhibitor of cholinergic receptors in rat striatal membranes. Chromatographic methods have been used to identify the presence of this substance in rat striatal membranes and acid complexes have been used for its purification.

• Brand: Biosynth

Chemical properties

• Molecular weight: 157.21 g/mol
• Formula: C₈H₁₅NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C8H15NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h7,9H,2-6H2,1H3/t7-/m1/s1
• InChI key: InChIKey=XIWBSOUNZWSFKU-SSDOTTSWSA-N
• SMILES: CCOC(=O)[C@@H]1CCCNC1