Ethyl 8-Bromooctanoate
CAS: 29823-21-0
Ref. 3D-FE45731
| 10g | 95.00 € | ||
| 25g | 131.00 € | ||
| 50g | 223.00 € | ||
| 100g | 353.00 € | ||
| 250g | 491.00 € |
Product Information
- 8-Bromo octanioic acid ethyl ester
- 8-Bromocaprylic acid ethyl ester
- Caprylic acid, η-bromo-, ethyl ester
- NSC 100182
- Octanoic acid, 8-bromo-, ethyl ester
Ethyl 8-bromooctanoate is a lipophilic brominated compound that binds to the bromodomains of the nuclear factor kappa B (NFκB) protein and inhibits its transcriptional activity. It also possesses antiproliferative activity in vitro, with some selectivity for cancer cells. The inhibition of NFκB transcriptional activity by ethyl 8-bromooctanoate may be due to the ability of this molecule to interfere with the formation of a complex between the bromodomain and the inhibitory domain of NFκB. It has been shown that oxetane derivatives can be used as starting materials for synthesis of ethyl 8-bromooctanoate. The synthetic scheme starts from commercially available biphenyl and chloroformates, followed by esterification reactions to produce diethyl esters. Bromination reactions are then carried out in order to produce the final product.
Chemical properties
Technical inquiry about: 3D-FE45731 Ethyl 8-Bromooctanoate
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