(R)-(-)-a-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]benzeneacetic Acid

CAS: 63422-71-9

Ref. 3D-FE60111

Product Information

• Name: (R)-(-)-a-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]benzeneacetic Acid
• Synonyms: (R)-(-)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetic Acid
• Brand: Biosynth
• Description: (R)-(-)-a-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]benzeneacetic Acid is an inhibitor of the enzyme histamine N-methyltransferase (HNMT), which is responsible for the synthesis of histamine. The inhibition of HNMT leads to a decrease in histamine levels and therefore has been used as a treatment for chronic prostatitis, lacrimal gland, and energy efficiency. Histamine N-methyltransferase also participates in the regulation of apoptosis by methylating proapoptotic proteins like Bax, so inhibition can lead to an increase in apoptosis. This chemical is also able to bind with chloride ions and form diphenyl ethers through a reaction solution, which are known to have anticancer properties.

Chemical properties

• Molecular weight: 319.31 g/mol
• Formula: C₁₅H₁₇N₃O₅
• Purity: Min. 98 Area-%
• Color/Form: Powder