Ethyl 2-hydroxy-5-methoxybenzoate

CAS: 22775-40-2

Ref. 3D-FE71080

Product Information

• Name: Ethyl 2-hydroxy-5-methoxybenzoate
• Synonyms: 2-Hydroxy-5-methoxy-benzoic acid ethyl ester, Benzoic acid, 2-hydroxy-5-methoxy-, ethyl ester, Brn 2095070, Ethyl 2-Hydroxy-5-Methoxybenzoate, S 29, Salicylic acid, 5-methoxy-, ethyl ester, m-Anisic acid, 6-hydroxy-, ethyl ester, m-Anisic acid, 6-hydroxy-, ethyl ester (8CI), Ethyl 5-methoxysalicylate

Description

Ethyl 2-hydroxy-5-methoxybenzoate (EHMB) is a phenolic compound that belongs to the group of salicylic acid. It is a natural product present in crucifers such as cabbage, broccoli, and cauliflower. EHMB has been shown to induce apoptosis in human leukemia cells through the inhibition of DNA methylation. The results showed that EHMB induces apoptosis in human leukemia cells by targeting the epigenetic regulator protein MLL1, which inhibits DNA methyltransferase 1 activity and leads to decreased levels of 5mC. EHMB also induces apoptosis in lung cancer cells by inhibiting cell proliferation and inducing cell death through the inhibition of GTPase activity, which leads to decreased levels of cyclin D1 and increased levels of p27. EHMB also regulates stem cell function by modulating gene expression; it has been shown that this compound can promote stem cell-like properties in mouse embryonic fibrobl

• Brand: Biosynth

Chemical properties

• Molecular weight: 196.2 g/mol
• Formula: C₁₀H₁₂O₄
• Purity: Min. 95%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C10H12O4/c1-3-14-10(12)8-6-7(13-2)4-5-9(8)11/h4-6,11H,3H2,1-2H3
• InChI key: InChIKey=QFDVMOCQOGCDKA-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cc(OC)ccc1O