Eupatilin

CAS: 22368-21-4

Ref. 3D-FE73950

Product Information

• Name: Eupatilin
• Synonyms: 2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one, 2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-chromen-4-one, 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-, 5,7-Dihydroxy-3′,4′,6-trimethoxyflavone, 5,7-Dihydroxy-6,3′,4′-trimethoxyflavone, Flavone, 5,7-dihydroxy-3′,4′,6-trimethoxy-, NSC 122413, Stillen

Description

2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one is a compound that has been shown to have renal protective effects. It binds to the Bcl-2 protein and prevents it from inhibiting apoptosis. This inhibits the activation of δ receptors, which are responsible for regulating insulin sensitivity in the kidney. The antihyperglycemic effect of this compound is demonstrated by its ability to inhibit glucose uptake in adipocytes and hepatocytes. 2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxychromen-4-one also has an antifibrotic effect and can be used as a drug for brain diseases such as Alzheimer’s disease and Parkinson’s disease. This compound binds to dna and inhibits cell cycle progression by inhibiting the action of topoisomerase II. Drug interactions

• Brand: Biosynth

Chemical properties

• Molecular weight: 344.32 g/mol
• Formula: C₁₈H₁₆O₇
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C18H16O7/c1-22-12-5-4-9(6-14(12)23-2)13-7-10(19)16-15(25-13)8-11(20)18(24-3)17(16)21/h4-8,20-21H,1-3H3
• InChI key: InChIKey=DRRWBCNQOKKKOL-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2cc(=O)c3c(O)c(OC)c(O)cc3o2)cc1OC