5-Formyluracil

CAS: 1195-08-0

Ref. 3D-FF07192

Product Information

• Name: 5-Formyluracil
• Synonyms: 1,2,3,4-Tetrahydro-2,4-dioxo-5-pyrimidinecarboxaldehyde, 2,4(1H,3H)-Pyrimidinedione, 5-formyl-, 2,4-Dihydroxy-5-formylpyrimidine, 2,4-Dihydroxy-pyrimidine-5-carbaldehyde, 2,4-Dihydroxypyrimidine-5-carbaldehyde, 2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbaldehyde, 2,4-Dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxaldehyde, 2,4-Dioxo-1H-pyrimidine-5-carbaldehyde, 5-, 5-Pyrimidinecarboxaldehyde, 5-Pyrimidinecarboxaldehyde, 1,2,3,4-tetrahydro-2,4-dioxo-, Immureg, NSC 197200, NSC 241524, Pyrimidinecarboxaldehyde, Uracil-5-carboxaldehyde

Description

5-Formyluracil is a cytotoxic agent that has been shown to be effective against cancer tissues. It is genotoxic, and this activity is due to the pyrazole ring in its structure, which can react with DNA bases. 5-Formyluracil also inhibits the polymerase chain reaction (PCR) by preventing DNA synthesis. The mechanism of action of 5-formyluracil involves its ability to form covalent bonds with DNA bases and inhibit enzyme activities. This drug has been shown to have a mode of action similar to that of cisplatin and other platinum-containing compounds, but without the side effects associated with cisplatin therapy. The analytical method for determining 5-formyluracil levels in tissue is by gas chromatography/mass spectrometry (GC/MS).

• Brand: Biosynth

Chemical properties

• Molecular weight: 140.1 g/mol
• Formula: C₅H₄N₂O₃
• Purity: Min. 95%
• Color/Form: Powder