4-Fluorophenyl isocyanate
CAS: 1195-45-5
Ref. 3D-FF07776
| 2g | 136.00 € | ||
| 5g | 189.00 € | ||
| 10g | 307.00 € | ||
| 25g | 407.00 € | ||
| 50g | 646.00 € |
Product Information
- 1-Fluoro-4-Isocyanatobenzene
- 4-Fluoro-1-isocyanatobenzene
- 4-Fluoroisocyanatobenzene
- 4-Flurophenyl isocyanate
- Benzene, 1-fluoro-4-isocyanato-
- Isocyanic acid, p-fluorophenyl ester
- NSC 82348
- p-Fluorobenzene isocyanate
- p-Fluorophenyl isocyanate
4-Fluorophenyl isocyanate is a hydroxylated derivative of phenyl isocyanate. It has been shown to have anticancer activity, with an IC50 value of about 50 μM. 4-Fluorophenyl isocyanate can be synthesized by reacting 3-bromopropylamine hydrobromide with hydrogen fluoride in the presence of a carbodiimide. The reaction can be optimized by adding epoxides or carbodiimides, and the best conditions are found to be at pH 10 and room temperature. 4-Fluorophenyl isocyanate binds to the MT2 receptor which leads to activation of G proteins, resulting in increased intracellular cAMP levels.
Chemical properties
Technical inquiry about: 3D-FF07776 4-Fluorophenyl isocyanate
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