Product Information
Name:Fiacitabine
Brand:Biosynth
Description:Fiacitabine is an antimicrobial agent that inhibits microbial growth by binding to the ribosomal 30S subunit and blocking protein synthesis. It is a prodrug that is converted to 5-fluorocytosine (5FC) in the liver, where it inhibits the activity of the enzyme dihydropyrimidine dehydrogenase, thereby interfering with DNA replication. Fiacitabine has been shown to be effective against infections caused by bacteria and fungi. In vitro studies have shown that fiacitabine binds to toll-like receptor 4 (TLR4), which may lead to its cytostatic effects. Fiacitabine also inhibits proliferation of HL60 cells in a dose-dependent manner.
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Chemical properties
Molecular weight:371.1 g/mol
Formula:C9H11FIN3O4
Purity:Min. 95%
Technical inquiry about: Fiacitabine
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