3-(4-Fluorobenzoyl)propionic acid

CAS: 366-77-8

Ref. 3D-FF10688

Product Information

• Name: 3-(4-Fluorobenzoyl)propionic acid
• Synonyms: 3-(4-Fluorobenzoyl)propanoic acid, 3-(p-Fluorobenzoyl)propionic acid, 4-(4-Fluorophenyl)-4-Oxobutanoic Acid, 4-(4-Fluorophenyl)-4-oxobutyric acid, 4-Fluoro-γ-oxobenzenebutanoic acid, 4-Fluorobenzoylpropionic acid, 4-Oxo-4-(p-fluorophenyl)butyric acid, Ba 2833, Benzenebutanoic acid, 4-fluoro-γ-oxo-, Haloperidol metabolite III, NSC 408180, Propionic acid, 3-(p-fluorobenzoyl)-, β-(4-Fluorobenzoyl)propionic acid, β-(p-Fluorobenzoyl)propionic acid, γ-(4-Fluorophenyl)-γ-oxobutanoic acid

Description

3-(4-Fluorobenzoyl)propionic acid (3FBP) is a novel, orally active dopamine D4 receptor agonist. 3FBP binds to the D4 receptor with high affinity and has been shown to have potent antinociceptive effects in CD-1 mice. The compound has also been shown to be effective in reducing locomotor activity in rats, as well as inducing motor impairment and catalepsy in mice. 3FBP does not produce any significant changes in striatal dopamine levels, suggesting that it may have a different mechanism of action than traditional dopaminergic drugs.

• Brand: Biosynth

Chemical properties

• Molecular weight: 196.18 g/mol
• Formula: C₁₀H₉FO₃
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C10H9FO3/c11-8-3-1-7(2-4-8)9(12)5-6-10(13)14/h1-4H,5-6H2,(H,13,14)
• InChI key: InChIKey=WUYWHIAAQYQKPP-UHFFFAOYSA-N
• SMILES: O=C(O)CCC(=O)c1ccc(F)cc1