FA-Phe-Gly-Gly-OH

CAS: 64967-39-1

Ref. 3D-FF110859

Product Information

• Name: FA-Phe-Gly-Gly-OH
• Synonyms: FAPGG, N-(3-(2-furyl)acryloyl)-phe-gly-gly, N-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutyryl]-L-leucine, N-[(2E)-3-furan-2-ylprop-2-enoyl]-L-phenylalanylglycylglycine, Arg-Gly-Pro-Phe-Pro-Ile, Arginylglycylprolylphenylalanylprolylisoleucine, Isoleucine, Arginylglycylprolylphenylalanylprolyl-, Fapgg
• CAS: 64967-39-1

Description

FA-Phe-Gly-Gly-OH is a peptide with angiotensin II inhibitory properties. It has been shown that FA-Phe-Gly-Gly-OH inhibits the enzyme activity of angiotensin converting enzyme (ACE) and prevents the formation of angiotensin II, which causes blood vessel constriction. The inhibitory effects of FA-Phe-Gly-Gly-OH on ACE are reversible and competitive, which is different from other ACE inhibitors that are irreversible and noncompetitive. This peptide also has antioxidative properties, due to its ability to scavenge reactive oxygen species (ROS). This peptide can be hydrolysed by esterases or proteases in vitro or in vivo.

• Brand: Biosynth

Chemical properties

• Molecular weight: 399.4 g/mol
• Formula: C₂₀H₂₁N₃O₆
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C20H21N3O6/c24-17(9-8-15-7-4-10-29-15)23-16(11-14-5-2-1-3-6-14)20(28)22-12-18(25)21-13-19(26)27/h1-10,16H,11-13H2,(H,21,25)(H,22,28)(H,23,24)(H,26,27)/b9-8+/t16-/m0/s1
• InChI key: InChIKey=ZDLZKMDMBBMJLI-FDMDGMSGSA-N
• SMILES: O=C(O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)/C=C/c1ccco1