3-Fluorophenyl boronic acid

CAS: 768-35-4

Ref. 3D-FF12163

Product Information

• Name: 3-Fluorophenyl boronic acid
• Synonyms: (3-Fluorophenyl-1-yl)boronic acid, 3-Fluoro Phenylboric Acid, 3-Fluorobenzeneboronic Acid, 3-Fluorobenzeneboronic Acid/3-Fluorophenylboronic Acid, 3-Fluorophenylbornic Acid, 3-Fluorophenylboroic acid, Akos Brn-0105, B-(3-Fluorophenyl)boronic acid, Benzeneboronic acid, m-fluoro-, Boronic acid, (3-fluorophenyl)-, Boronic acid, B-(3-fluorophenyl)-, Ethane-1,2-Diylbis[Bis(Pentafluorophenyl)Phosphane], M-Fluorophenylboronic Acid, Rarechem Ah Pb 0217

Description

3-Fluorophenyl boronic acid is a chemical compound that contains a 3-fluorophenyl group and a boron atom. It can be synthesized in the Suzuki coupling reaction of 2,6-difluoroaniline and phenylboronic acid. 3-Fluorophenyl boronic acid has been used to study the binding of human receptors, such as alpha1 adrenergic receptor and beta2 adrenergic receptor, by using nuclear magnetic resonance spectroscopy. This compound also inhibits bacterial growth and glucose metabolism in diabetic patients.
3-Fluorophenyl boronic acid has hydrophobic properties that allow it to bind to the hydrophobic region on the surface of proteins, inhibiting their function. It is also reversible due to its covalent nature. The compound can be metabolized by humans through hydrolysis or oxidation reactions that produce an acetic acid derivative.

• Brand: Biosynth

Chemical properties

• Molecular weight: 139.92 g/mol
• Formula: C₆H₆BFO₂
• Purity: Min. 95%
• Color/Form: Powder