Product Information
Name:Fmoc-Ser(tBu)-OH
Synonyms:
- Fmoc-O-tert-butyl-L-serineN-(9-Fluorenylmethoxycarbonyl)-O-tert-butyl-L-serineFmoc-L-Ser(tBu)-OH
Brand:Biosynth
Description:Fmoc-Ser(tBu)-OH is a synthetic amino acid that is used in the synthesis of degarelix acetate, an amide ester of the vasodilator, prostaglandin F2α. Degarelix acetate binds to the fibrinogen receptor on the surface of cells and inhibits platelet aggregation. This drug has been shown to be effective in treating prostate cancer by inhibiting epidermal growth factor receptor signaling. It also has immune modulating effects by binding to monoclonal antibodies and altering antibody responses. Fmoc-Ser(tBu)-OH is synthesized from the amino acid serine and t-butyl alcohol, which are combined with trifluoroacetic acid (TFA) and hydroxyl group. The resulting product is then reacted with dansyl chloride or benzoyl chloride (BzCl), which cleaves off one carboxylic acid group from serine, forming an
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:383.44 g/mol
Formula:C22H25NO5
Purity:Min. 98 Area-%
Color/Form:White Off-White Powder
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