Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Ref. 3D-FF15778

Product Information

• Name: Fmoc-Thr(tBu)-OH
• Synonyms: Fmoc-O-tert-butyl-L-threonineFmoc-L-Thr(tBu)-OH, (2S,3R)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-(tert-butoxy)butanoic acid, (2S,3R)-3-tert-Butoxy-2-[[[[9H-fluoren-9-yl]methoxy]carbonyl]amino)butanoic acid, (2S,3R)-3-tert-butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoate, <span class="text-smallcaps">L</span>-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, FMOC-O-tert-Butyl-L-threonine, Fmoc-L-Thr(tBu)-OH, Fmoc-Thr(OtBu)-OH, N-(9-Fluorenylmethoxycarbonyl)-O-tert-butylthreonine, O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-threonine, O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine, O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]threonine

Description

Fmoc-Thr(tBu)-OH is an ester hydrochloride that is synthesized by reacting the amino acid, Fmoc-Thr(tBu) with trifluoroacetic acid. It has been used to synthesize a cyclic peptide with a protonated amide group, which allows for stereoselective synthesis of the chloride. This product has shown to be resistant to hydrolysis by atosiban and carbonyl oxygens, and also binds to mammalian cell receptors.

• Brand: Biosynth

Chemical properties

• Molecular weight: 397.46 g/mol
• Formula: C₂₃H₂₇NO₅
• Purity: Min. 98 Area-%
• Color/Form: White Powder
• InChI: InChI=1S/C23H27NO5/c1-14(29-23(2,3)4)20(21(25)26)24-22(27)28-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20H,13H2,1-4H3,(H,24,27)(H,25,26)/t14-,20+/m1/s1
• InChI key: InChIKey=LZOLWEQBVPVDPR-VLIAUNLRSA-N
• SMILES: C[C@@H](OC(C)(C)C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O