Fmoc-Gly-OH

CAS: 29022-11-5

Ref. 3D-FF15873

Product Information

• Name: Fmoc-Gly-OH
• Synonyms: Fmoc-glycine, 2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid, 2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]ethanoic acid, 307: PN: US20070042401 PAGE: 38 claimed protein, 999: PN: WO2006135786 PAGE: 71 claimed protein, Fluorene-9-methanol, N-ester with N-carboxyglycine, Fmoc glycine, Glycine, N-carboxy-, N-(fluoren-9-ylmethyl) ester, N-(9-Fluorenylmethoxycarbonyl)glycine, N-Fluorenylmethoxycarbonylglycine, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycin, N-[(9H-fluoren-9-ilmetoxi)carbonil]glicina, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycine, N-[(9H-fluorene-9-ylmethoxy)carbonyl]glycine, Npc 14692, Nsc 334288, [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid

Description

Fmoc-Gly-OH is a peptide that has been shown to have anti-inflammatory properties. It inhibits the production of inflammatory cytokines by binding to the receptor for IL-1β on du145 cells, which are prostate cancer cells. The synthesis of Fmoc-Gly-OH is achieved through an ester hydrochloride and amide bond formation. This synthesis method is not efficient and requires high amounts of reagents and solvents. Fmoc-Gly-OH has been shown to be effective in inhibiting the inflammatory response in human serum with a dose of 10 μM, but it does not inhibit inflammation in chronic exposure studies with rats or mice.!--

• Brand: Biosynth

Chemical properties

• Molecular weight: 297.31 g/mol
• Formula: C₁₇H₁₅NO₄
• Purity: Min. 98 Area-%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C17H15NO4/c19-16(20)9-18-17(21)22-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,18,21)(H,19,20)
• InChI key: InChIKey=NDKDFTQNXLHCGO-UHFFFAOYSA-N
• SMILES: O=C(O)CNC(=O)OCC1c2ccccc2-c2ccccc21