Fmoc-L-Glu-OtBu

CAS: 84793-07-7

Ref. 3D-FF15874

Product Information

• Name: Fmoc-L-Glu-OtBu
• Synonyms: Fmoc-L-glutamic acid α-tert-butyl ester
• Brand: Biosynth
• Description: Fmoc-L-Glu-OtBu is a synthetic ligand that is used as a fluorescent probe in vivo. It has been shown to bind to semaglutide with high affinity, and it can be used to study the function of semaglutide in the cell. Fmoc-L-Glu-OtBu has also been found to have an inhibitory effect on cancer cells. This ligand can be synthesized by solid-phase synthesis and purified by column chromatography. The purity of Fmoc-L-Glu-OtBu is confirmed by elemental analysis, and its impurities are determined by fluorescence spectroscopy. The carboxylate group of Fmoc-L-Glu-OtBu is activated with sulfuric acid to form the corresponding active ester, which can then be conjugated with other molecules.

Chemical properties

• Molecular weight: 425.47 g/mol
• Formula: C₂₄H₂₇NO₆
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C24H27NO6/c1-24(2,3)31-22(28)20(12-13-21(26)27)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,27)/t20-/m0/s1
• InChI key: InChIKey=GOPWHXPXSPIIQZ-FQEVSTJZSA-N
• SMILES: CC(C)(C)OC(=O)[C@H](CCC(=O)O)NC(=O)OCC1c2ccccc2-c2ccccc21