2-Fluoro-6-iodobenzonitrile

Ref. 3D-FF16011

Product Information

• Name: 2-Fluoro-6-iodobenzonitrile
• Synonyms: 2-Iodo-6-fluoro benzonitrile2-Cyano-3-fluoro-1-iodobenzene
• Brand: Biosynth
• Description: 2-Fluoro-6-iodobenzonitrile is a potent inhibitor of the BCR-ABL tyrosine kinases. It binds to the ATP binding site of these enzymes and inhibits the catalytic activity, leading to cell death. 2-Fluoro-6-iodobenzonitrile has been shown to have potent inhibitory activity against mutant forms of BCR-ABL, including T315I and T315I/T2535I, which are resistant to imatinib. 2-Fluoro-6-iodobenzonitrile has also been shown to have anti-proliferative activities in cancer cells and can be used as an anticancer agent.

Chemical properties

• Molecular weight: 247.01 g/mol
• Formula: C₇H₃FIN
• Purity: Min. 95%