Felbinac

CAS: 5728-52-9

Ref. 3D-FF23234

Product Information

• Name: Felbinac
• Synonyms: [1,1'-Biphenyl]-4-acetic acid4-Carboxymethylbiphenyl4-Phenylphenylacetic acid4-Biphenylacetic acid, ([1,1′-Biphenyl]-4-yl)acetic acid, 2-(4-Phenylphenyl)acetic acid, 2-(Biphenyl-4-yl)acetic acid, 2-(Diethylamino)Ethyl 2-Hydroxybiphenyl-3-Carboxylate, 2-([1,1′-Biphenyl]-4-yl)acetic acid, 2-Diethylaminoethyl 3-Phenylsalicylate, 4-Biphenylacetic biphenyl-4-ylacetic acid, 4-Biphenylylacetic acid, 4-Carboxymethylbiphenyl, 4-Diphenylacetic Acid, 4-Phenylphenylacetic Acid, Acetic acid, (4-biphenylyl)-, Biphenyl-4-Acetic Acid, Biphenyl-4-Ylacetate, Biphenyl-4-yl-acetic acid, Ci 83544, Cl 83544, Felbion 35, L 141, Ljc 10141, Ly 61017, NSC 16284, P-Biphenylacetic acid, Seltouch, Traxam, Xenysalate, [1,1'-Biphenyl]-4-Acetic Acid, p-Biphenylylacetic acid, 4-Biphenylacetic acid

Description

Felbinac is a nonsteroidal anti-inflammatory drug with analgesic and antipyretic properties. It is a racemic mixture of the enantiomers R-(+)-felbinac and S-(-)-felbinac. The chemical structure of felbinac is similar to that of aspirin, but it has a lower level of side effects. Felbinac inhibits prostaglandin synthesis by blocking cyclooxygenase and lipoxygenase reactions. It also has anti-inflammatory activity, and reduces the production of pro-inflammatory mediators such as PGE2 levels in human serum, which may be due to its ability to inhibit signal pathways in the cell nucleus.
A number of toxicological studies have been conducted using felbinac on rats, mice, rabbits, and dogs. No major toxicological effects were observed at doses up to 1000 mg/kg body weight for 28 days.

• Brand: Biosynth

Chemical properties

• Molecular weight: 212.24 g/mol
• Formula: C₁₄H₁₂O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16)
• InChI key: InChIKey=QRZAKQDHEVVFRX-UHFFFAOYSA-N
• SMILES: O=C(O)Cc1ccc(-c2ccccc2)cc1