Fenbendazole

CAS: 43210-67-9

Ref. 3D-FF23242

Product Information

• Name: Fenbendazole
• Synonyms: N-[6-(Phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester, (5-Phenylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester, 2-(Methoxycarbonylamino)-5-(phenylthio)benzimidazole, Axilur, Carbamic acid, N-[6-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester, Carbamic acid, [5-(phenylthio)-1H-benzimidazol-2-yl]-, methyl ester, Febendazole, Fenbendazol, Fenbion, Hoe 881, Hoe-881V, Methyl 5-(phenylthio)-2-benzimidazolecarbamate, Methyl [5-(phenylthio)-1H-benzimidazol-2-yl]carbamate, Methyl-5-Phenyl-Thio-2-Benzimidazole Carbamate, Panacur, Panacur AquaSol, Phenthioimidazole, Safe-Guard, Vigisol, [5-(Phenylthio)-1H-Benzimidazol-2-Yl]Carbamic Acid, Methyl Ester, methyl N-(5-phenylsulfanyl-3H-benzoimidazol-2-yl)carbamate, methyl [6-(phenylsulfanyl)-1H-benzimidazol-2-yl]carbamate

Description

Fenbendazole is an anthelmintic drug used for the treatment of parasitic worm infections. Fenbendazole inhibits the growth of parasites by inhibiting their ability to reproduce, which may be due to its effects on sorbitol dehydrogenase and matrix effect. Fenbendazole has minimal toxicity in laboratory animals and can be administered orally or intravenously. The compound also has a low potential for drug interactions with other drugs that are metabolized by cytochrome P450 enzymes. Fenbendazole has been shown to have long-term toxicity in rats, but not dogs, and is not carcinogenic in mice. Fenbendazole has also been shown to bind to iron in the gastrointestinal tract when given orally, preventing uptake into the body and causing damage to intestinal cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 299.35 g/mol
• Formula: C₁₅H₁₃N₃O₂S
• Purity: Min. 97.5 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)
• InChI key: InChIKey=HDDSHPAODJUKPD-UHFFFAOYSA-N
• SMILES: COC(=O)Nc1nc2ccc(Sc3ccccc3)cc2[nH]1