Florfenicol

CAS: 73231-34-2

Ref. 3D-FF23306

Product Information

• Name: Florfenicol
• Synonyms: 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide, 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide, 2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide, 2,2-dichloro-N-{1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfanyl)phenyl]ethyl}acetamide, Acetamide, 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-, Acetamide, 2,2-dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,S*)]-, Aquafen, Aquaflor, Flofenicol, Flonicol, Florfeniol, Florgane, Floron, Nuflor, Sch 25298, Selectan, Topazone

Description

Florfenicol is a broad-spectrum antibiotic that belongs to the group of florfenicol. It is used in veterinary medicine to treat bacterial infections in animals, including those caused by salmonella, streptococcus, and mycoplasma. Florfenicol has been shown to have an inhibitory effect on the growth of tetracycline-resistant bacteria. Florfenicol binds reversibly to the 23S ribosomal RNA in the 50S subunit of bacteria and inhibits protein synthesis. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme ribosome that is required for translation, inhibiting protein synthesis and cell division. The rate constant for this reaction has been determined using a combination of analytical methods, including chromatographic analysis and colloidal gold electrophoresis. Florfenicol also has anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 358.21 g/mol
• Formula: C₁₂H₁₄Cl₂FNO₄S
• Purity: Min. 98 Area-%
• Color/Form: White Powder