4-Fluoroquinoline

Ref. 3D-FF23487

Product Information

• Name: 4-Fluoroquinoline
• Brand: Biosynth
• Description: 4-Fluoroquinoline is a molecule that is used in the synthesis of fluorinated drugs. It has been shown to be tumorigenic in mice and rats and is thought to act by alkylating DNA. 4-Fluoroquinoline has been used for the preparation of radiotracers for positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging. This compound can also be used as an intercalator and labeled with a radioisotope for use as a pharmaceutical or diagnostic agent. The 4-fluoroquinolines exhibit high affinity for nucleophilic sites on DNA, which leads to crosslinking and stabilization of the DNA strand. The chemical structures of these molecules are easily analyzed using chromatographic methods. Assays have been developed that allow detection of 4-fluoroquinoline in urine samples.

Chemical properties

• Molecular weight: 147.15 g/mol
• Formula: C₉H₆FN
• Purity: Min. 95%