Fmoc-L-Ser-OH

CAS: 73724-45-5

Ref. 3D-FF33216

Product Information

• Name: Fmoc-L-Ser-OH
• Synonyms: N-Fmoc-L-serine monohydrate, N-(9-Fluorenylmethoxycarbonyl)-L-serine, Fmoc-Ser-OH, N-Fmoc-L-serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine, (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-hydroxypropanoate

Description

Fmoc-L-Ser-OH is a synthetic peptide that belongs to the group of glycopeptides. It is used as a model for such compounds and has been shown to have antimicrobial activity in vitro against gram-positive bacteria, especially Staphylococcus epidermidis. This compound was synthesized from 3-mercaptopropionic acid and chloride in the presence of hydroxyl groups and epidermal growth factor. The synthetic pathway can be divided into three steps: (1) condensation of 3-mercaptopropionic acid with hydrochloric acid to yield 3-mercaptoacrylic acid; (2) esterification of 3-mercaptoacrylic acid with glycine to form Fmoc-L-Ser; and (3) deprotection of Fmoc protecting group.
Fmoc-L-Ser has also been shown to have antiestrogenic effects, which may be due to

• Brand: Biosynth

Chemical properties

• Molecular weight: 327.33 g/mol
• Formula: C₁₈H₁₇NO₅
• Purity: Min. 95%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C18H17NO5/c20-9-16(17(21)22)19-18(23)24-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16,20H,9-10H2,(H,19,23)(H,21,22)/t16-/m0/s1
• InChI key: InChIKey=JZTKZVJMSCONAK-INIZCTEOSA-N
• SMILES: O=C(N[C@@H](CO)C(=O)O)OCC1c2ccccc2-c2ccccc21