Fmoc-D-Tyr(tBu)-OH

CAS: 118488-18-9

Ref. 3D-FF33483

Product Information

• Name: Fmoc-D-Tyr(tBu)-OH
• Synonyms: Fmoc-D-Tyr(But)-OH, O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-tyrosine, Fmoc-D-Tyr(OtBu)-OH

Description

Fmoc-D-Tyr(tBu)-OH is a high-affinity, potent, and selective antagonist of the fatty acid binding protein (FABP). It has antimicrobial peptide activity in biological assays. The biological properties of Fmoc-D-Tyr(tBu)-OH are activated by protease activity, which results in the cleavage of the cyclic peptide backbone to form an anti-bacterial peptide with minimal toxicity. This compound can be used as a radionuclide probe for integrin receptors, and has been shown to have a high affinity for integrin αvβ3. Fmoc-D-Tyr(tBu)-OH is synthesized using an asymmetric synthesis that results in the formation of a disulfide bond.

• Brand: Biosynth

Chemical properties

• Molecular weight: 459.53 g/mol
• Formula: C₂₈H₂₉NO₅
• Purity: Min. 95%
• InChI: InChI=1S/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)/t25-/m1/s1
• InChI key: InChIKey=JAUKCFULLJFBFN-RUZDIDTESA-N
• SMILES: CC(C)(C)Oc1ccc(C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)cc1