Product Information
Name:Fmoc-O-benzylphospho-L-serine
Synonyms:
- Fmoc-L-Ser(HPO3Bzl)-OH
Brand:Biosynth
Description:Fmoc-O-benzylphospho-L-serine is a fmoc-protected phosphoserine derivative for efficient synthesis of phosphoserine-containing peptides via standard fmoc SPPS. Compatible with common activators such as PyBOP or TBTU, it remains stable during piperidine deprotection and enables incorporation of multiple phosphoserine residues, for example successful syntheses of phospholamban and human salivary statherin. In certain cases, β-piperidinylalanine formation may occur during N-terminal Ser(PO(OBzl)OH) Fmoc deprotection, especially under microwave conditions.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:497.43 g/mol
Formula:C25H24NO8P
Purity:Min. 97 Area-%
Color/Form:White Off-White Powder
InChI:InChI=1S/C25H24NO8P/c27-24(28)23(16-34-35(30,31)33-14-17-8-2-1-3-9-17)26-25(29)32-15-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h1-13,22-23H,14-16H2,(H,26,29)(H,27,28)(H,30,31)/t23-/m0/s1
InChI key:InChIKey=ZBPUWGDUVAAWJY-QHCPKHFHSA-N
SMILES:O=C(N[C@@H](COP(=O)(O)OCc1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21
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