Fmoc-S-trityl-L-penicillamine

CAS: 201531-88-6

Ref. 3D-FF47878

Product Information

• Name: Fmoc-S-trityl-L-penicillamine
• Synonyms: Fmoc-L-Pen(Trt)-OHFmoc-S-trityl-b,b-dimethyl-L-Cys-OH
• Brand: Biosynth
• Description: Fmoc-S-trityl-L-penicillamine is a coordination compound that contains a thiolate and amide group. It has been used as a model system for studying the interaction between proteins and metal ions, with the cyclic structure mimicking the active site of enzymes. The coordination of Fmoc-S-trityl-L-penicillamine to proteins is affected by trypsin, an enzyme that cleaves peptides at carboxyl side chains. Trypsin can also lead to dehydration of Fmoc-S-trityl-L-penicillamine, forming an eliminations product. This compound also reacts with lysine residues in proteins, resulting in an alkene byproduct that can be removed by hydrogenation.

Chemical properties

• Molecular weight: 613.77 g/mol
• Formula: C₃₉H₃₅NO₄S
• Purity: Min. 95%
• Color/Form: Powder