Fusaric acid

CAS: 536-69-6

Ref. 3D-FF52452

Product Information

• Name: Fusaric acid
• Synonyms: 2-Pyridinecarboxylic acid, 5-butyl-, 5-Butyl-2-picolinic acid, 5-Butyl-2-pyridinecarboxylic acid, 5-Butylpicolinic acid, 5-Butylpyridine-2-Carboxylate, 5-Butylpyridine-2-Carboxylic Acid, 5-n-Butylpyridine-2-carboxylic acid, Butylpicolinic acid, Fusaric Acid From Gibberella Fujikuroi, NSC 135043, NSC 19870, Picolinic acid, 5-butyl-

Description

Fusaric acid is a metabolite of the natural product fusarin. It is formed by the enzymatic hydroxylation of dopamine and has been shown to inhibit the production of picolinic acid, which is involved in the synthesis of NAD. Fusaric acid also inhibits tetracycline resistance in colorectal adenocarcinoma cells, leading to cell death. Fusaric acid has also been found to be effective against squamous carcinoma cells and thermal expansion in titration calorimetry experiments. The structural analysis of this compound showed that it has a planar geometry with a number of hydrogen bonding interactions.
FUSARIC ACID:
Fusaric acid is an inhibitor of dopamine β-hydroxylase (DBH) that was first isolated from fusarin, a natural product produced by some fungi species. It binds reversibly to DBH and blocks its activity, preventing the conversion of

• Brand: Biosynth

Chemical properties

• Molecular weight: 179.22 g/mol
• Formula: C₁₀H₁₃NO₂
• Color/Form: Off-White Powder