6-Fluoro-4-hydroxy-2-methylquinoline

Ref. 3D-FF54138

Product Information

• Name: 6-Fluoro-4-hydroxy-2-methylquinoline
• Synonyms: 6-Fluoro-2-methyl-4-quinolinol
• Brand: Biosynth
• Description: 6-Fluoro-4-hydroxy-2-methylquinoline is a diazoxide derivative that has vasorelaxant properties. It increases the cytosolic concentration of calcium ions and inhibits ATP-sensitive K+ channels, which results in relaxation of smooth muscle cells. 6-Fluoro-4-hydroxy-2-methylquinoline was shown to be effective in blocking the hyperglycemic response in pancreatic tissues by inhibiting glucose uptake. This drug also has been shown to have a significant effect on extracellular calcium ion concentrations. 6-Fluoro 4 hydroxy 2 methylquinoline is used as an experimental tool for studying the function of atp sensitive K+ channels in muscles and other tissues.

Chemical properties

• Molecular weight: 177.18 g/mol
• Formula: C₁₀H₈FNO
• Purity: Min. 95%
• InChI: InChI=1S/C10H8FNO/c1-6-4-10(13)8-5-7(11)2-3-9(8)12-6/h2-5H,1H3,(H,12,13)
• InChI key: InChIKey=BKXCHVFCJZJATJ-UHFFFAOYSA-N
• SMILES: Cc1cc(=O)c2cc(F)ccc2[nH]1