6-Fluoro-4-hydroxycoumarin

Ref. 3D-FF54298

Product Information

• Name: 6-Fluoro-4-hydroxycoumarin
• Synonyms: 6-Fluoro-4-hydroxy-2H-chromen-2-one
• Brand: Biosynth
• Description: 6-Fluoro-4-hydroxycoumarin is a synthetic anticoagulant that is used to prevent blood from clotting. It is a competitive inhibitor of the enzyme vitamin K epoxide reductase, which converts vitamin K to its active form, known as vitamin K epoxide. This chemical prevents the formation of vitamin K epoxide and, in turn, reduces the conversion of prothrombin to thrombin. The effect on prothrombin synthesis can lead to an increased risk of bleeding. 6-Fluoro-4-hydroxycoumarin has been shown to be effective in preventing thrombosis in patients with artificial heart valves or mechanical prosthetic heart valves.END>

Chemical properties

• Molecular weight: 180.13 g/mol
• Formula: C₉H₅FO₃
• Purity: Min. 95%
• InChI: InChI=1S/C9H5FO3/c10-5-1-2-8-6(3-5)7(11)4-9(12)13-8/h1-4,11H
• InChI key: InChIKey=JCOYNGQUPPGRNB-UHFFFAOYSA-N
• SMILES: O=c1cc(O)c2cc(F)ccc2o1