N-Formyl-Met-Leu-Phe

CAS: 59880-97-6

Ref. 3D-FF73395

Product Information

• Name: N-Formyl-Met-Leu-Phe
• Synonyms: 3: PN: WO2010089019 PAGE: 22 claimed protein, 4-(2-Aminoethyl)Phenol Hydrochloride (1:1), 4-Hydroxy-phenethylamine hydrochloride, <span class="text-smallcaps">L</smallcap>-Phenylalanine, N-[N-(N-formyl-<smallcap>L</smallcap>-methionyl)-<smallcap>L</span>-leucyl]-, <span class="text-smallcaps">L</smallcap>-Phenylalanine, N-formyl-<smallcap>L</smallcap>-methionyl-<smallcap>L</span>-leucyl-, For-Met-Leu-Phe-OH, Formyl-Met-Leu-Phe-OH, N-Formyl-<span class="text-smallcaps">L</smallcap>-methionyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</span>-phenylalanine, N-Formyl-Met-Leu-Phe-OH, N-Formyl-methionyl-leucyl-phenylalanine, N-formylmethionylleucylphenylalanine, NSC 350593

Description

N-Formyl-Met-Leu-Phe (NFML) is a hematopoietic growth factor that is found in human serum. It has been shown to induce chemotaxis and angiogenesis, as well as activate cytosolic calcium and camp levels, in polymorphonuclear leucocytes (PMN). NFML also induces the production of prostaglandin E2 (PGE2), which may be due to its ability to upregulate the expression of cyclooxygenase-2 (COX-2) in PMN. NFML has been shown to act as a chemokine for monoclonal antibody against toll-like receptor 4, which is activated by bacterial lipopolysaccharides.

• Brand: Biosynth

Chemical properties

• Molecular weight: 437.55 g/mol
• Formula: C₂₁H₃₁N₃O₅S
• Purity: Min. 95%