4-Fluoro-3-trifluoromethylphenylboronic acid

CAS: 182344-23-6

Ref. 3D-FF76266

Product Information

• Name: 4-Fluoro-3-trifluoromethylphenylboronic acid
• Synonyms: (4-Fluoro-3-Trifluoromethyl)Benzeneboronic Acid, 3-(Trifluoromethyl)-4-fluorophenylboronic acid, 3-Trifluoromethyl-4-Fluoro-Phenylboronic Acid, 4-Fluoro-(trifluoromethyl)phenylboronic Acid, 4-Fluoro-3-(trifluoromethyl)benzeneboronic acid 98%, 4-Fluoro-3-(trifluoromethyl)benzeneboronicacid98%, Akos Brn-1028, B-[4-Fluoro-3-(trifluoromethyl)phenyl]boronic acid, Boronic acid, B-[4-fluoro-3-(trifluoromethyl)phenyl]-, Boronic acid, [4-fluoro-3-(trifluoromethyl)phenyl]-, [4-Fluoro-3-(trifluoromethyl)phenyl]boronic acid

Description

4-Fluoro-3-trifluoromethylphenylboronic acid is a reagent that can be used in organic synthesis. It has high molecular weight and is not reactive with protons. The compound can be demethylated by treatment with base, and fluorine can be substituted with chlorine to form 4-chloro-3-trifluoromethylphenylboronic acid. This reagent is used for cross-coupling reactions, including Suzuki and Sonogashira couplings, at temperatures between -30°C and 120°C. 4-Fluoro-3-trifluoromethylphenylboronic acid reacts as a nucleophile and forms a transition state intermediate when reacting with an electrophile.

• Brand: Biosynth

Chemical properties

• Molecular weight: 207.92 g/mol
• Formula: C₇H₅BF₄O₂
• Purity: Min. 95%
• InChI: InChI=1S/C7H5BF4O2/c9-6-2-1-4(8(13)14)3-5(6)7(10,11)12/h1-3,13-14H
• InChI key: InChIKey=GUJYFCBXDUPORN-UHFFFAOYSA-N
• SMILES: OB(O)c1ccc(F)c(C(F)(F)F)c1