Product Information
- Estra-1,3,5(10)-triene-3,17-diol, 16-fluoro-, (16beta,17beta)-
16-Fluoroestradiol is a fluorinated form of estradiol that binds to the estrogen receptor. It has been shown to have high affinity for the receptor and is found in tissues such as breast, uterus, and vagina. 16-Fluoroestradiol has been used in cancer research to study uptake and metabolism of estrogens. The drug is metabolized by hydroxylation via cytochrome P450 enzymes and through the action of nucleophilic enzymes such as carboxylesterases. 16-Fluoroestradiol has also been shown to bind to muscle tissue, which may be due to its ability to inhibit uptake of glucose into cells.
Chemical properties
Technical inquiry about: 3D-FF77214 16-Fluoroestradiol
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