4-Fluoroandrostenedione

CAS: 98102-30-8

Ref. 3D-FF77712

Product Information

• Name: 4-Fluoroandrostenedione

Description

4-Fluoroandrostenedione is a synthetic, nonsteroidal compound that has been shown to be an effective androgen ablation agent. It binds to the androgen receptor, which prevents conversion of testosterone into dihydrotestosterone (DHT). 4-Fluoroandrostenedione has been used in clinical trials for the treatment of prostate cancer. This drug has also been shown to inhibit the production of estrogens by binding to the aromatase enzyme, which converts androgens into estrogens. Substitutions on the a-ring have been shown to increase its activity as an anti-cancer agent. 4-Fluoroandrostenedione can be synthesized from androstenedione by substituting a fluorine atom on one of the carbons in the a-ring.

• Brand: Biosynth

Chemical properties

• Molecular weight: 304.4 g/mol
• Formula: C₁₉H₂₅FO₂
• Purity: Min. 95%
• InChI: InChI=1S/C19H25FO2/c1-18-10-8-15(21)17(20)14(18)4-3-11-12-5-6-16(22)19(12,2)9-7-13(11)18/h11-13H,3-10H2,1-2H3/t11-,12-,13-,18+,19-/m0/s1
• InChI key: InChIKey=QBRBEAIYDMHSJE-KZQROQTASA-N
• SMILES: C[C@]12CC[C@H]3[C@@H](CCC4=C(F)C(=O)CC[C@@]43C)[C@@H]1CCC2=O