3-Fluorobenzyl isocyanate
CAS: 102422-56-0
Ref. 3D-FF96949
| 1g | 229.00 € | ||
| 2g | 343.00 € | ||
| 5g | 538.00 € | ||
| 250mg | 100.00 € | ||
| 500mg | 167.00 € |
Product Information
- 1-Fluoro-3-(isocyanatomethyl)benzene
- 5-Fluorobenzylisocyanate
- Benzene, 1-fluoro-3-(isocyanatomethyl)-
3-Fluorobenzyl isocyanate is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β). GSK-3β is a serine/threonine protein kinase that plays an important role in the regulation of glycogen metabolism, cell cycle progression, and apoptosis. 3-Fluorobenzyl isocyanate blocks the phosphorylation site on GSK-3β's ATP binding site and inhibits its activity. This drug also has inhibitory effects on x-ray irradiation induced hyperphosphorylation of tau protein in Alzheimer's disease patients. 3-Fluorobenzyl isocyanate has been shown to form co-crystals with oxadiazole derivatives, which may be due to their structural similarity. The co-crystal structure of 3-fluorobenzyl isocyanate and oxadiazole derivatives was determined using x-ray diff
Chemical properties
Technical inquiry about: 3D-FF96949 3-Fluorobenzyl isocyanate
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