Product Information
Name:STS 135
Controlled Product
Synonyms:
- 1-(5-Fluoropentyl)-N-tricyclo[3.3.1.1(3,7)]dec-1-yl-1H-indole-3-carboxamide
Brand:Biosynth
Description:STS-135 is a synthetic cannabinoid with potent agonist activity towards the CB1 and CB2 receptors (EC50= 13 nM and 51 nM, respectively). Its adamantyl carboxamide group is thought to increase affinity at the CB2 receptor1. In murine cells in vitro assays, STS-135 was shown to be more neurotoxic than other synthetic cannabinoid receptor agonists. In in vivo rodent models, it encourages the release of dopamine in the shell nucleus accumbens3. In line with other synthetic cannabinoid receptor agonists, it induces bradycardia and hypothermia in experimental rat models, as well as sensorimotor alterations and seizures in mice, which are prevented by inverse CB1 agonists1,2.
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Chemical properties
Molecular weight:382.51 g/mol
Formula:C24H31FN2O
Purity:Min. 95%
Technical inquiry about: STS 135
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