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methyl 4-[(chlorosulfonyl)methyl]benzoate
CAS: 130047-14-2
Ref. 3D-FFA04714
| 250mg | 347.00 € | ||
| 2500mg | 1,298.00 € |
Product Information
- Methyl 4-[(chlorosulfonyl)methyl]benzoate
- [4-(Methoxycarbonyl)phenyl]methanesulphonyl chloride
- [4-(Methoxycarbonyl)phenyl]methanesulphonyl chloride 95%
- Methyl 4-[(chlorosulphonyl)methyl]benzoate
Methyl 4-[(chlorosulfonyl)methyl]benzoate is a potent and selective inhibitor of nuclear receptors that are involved in the inflammatory response. It has been shown to inhibit tumor cell proliferation in a xenograft model. Methyl 4-[(chlorosulfonyl)methyl]benzoate inhibits the activity of nuclear receptors by binding to an allosteric site on their ligand-binding domain and preventing coactivator binding. This leads to reduced transcriptional activation, which inhibits the production of proinflammatory molecules. Methyl 4-[(chlorosulfonyl)methyl]benzoate is orally bioavailable and has been shown to have anti-tumor effects in mice with neuroblastoma tumors.
Chemical properties
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