L-Glutamic acid diethyl ester HCl

CAS: 1118-89-4

Ref. 3D-FG03049

Product Information

• Name: L-Glutamic acid diethyl ester HCl
• Synonyms: (S)-1,5-Diethoxy-1,5-dioxopentan-2-amine hydrochloride, (S)-Diethyl 2-aminopentanedioate hydrochloride, <span class="text-smallcaps">L</span>-Glutamic acid, 1,5-diethyl ester, hydrochloride (1:1), <span class="text-smallcaps">L</span>-Glutamic acid, diethyl ester, hydrochloride, Diethyl <span class="text-smallcaps">L</span>-glutamate hydrochloride, Diethyl Glutamate, Diethyl glutamate hydrochloride, Glu(oEt)2HCl, Glutamic acid diethyl ester hydrochloride, Glutamic acid, diethyl ester, hydrochloride, <span class="text-smallcaps">L</span>-, H-Glu(OEt)-OEt . HCl, H-Glu(OEt)-OEt・HCl, NSC 12960, NSC 17007, diethyl L-glutamate, diethyl L-glutamate hydrochloride, diethyl L-glutamate hydrochloride (1:1)

Description

L-glutamic acid diethyl ester hydrochloride (GDE) is an experimental drug that inhibits the activity of glutamic acid decarboxylase, an enzyme that catalyses the production of glutamate. GDE has been shown to decrease locomotor activity in rats and to cause neuronal death in cerebellar Purkinje neurons. It also has low potency as a neurotransmitter. L-Glutamic acid diethyl ester hydrochloride has been shown to be effective against autoimmune diseases and metabolic disorders, although it did not show significant effects on pharmacokinetic properties or glutamate levels in experimental models.

• Brand: Biosynth

Chemical properties

• Molecular weight: 239.7 g/mol
• Formula: C₉H₁₇NO₄·HCl
• Purity: Min. 95%
• Color/Form: Powder